Niclosamide
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Henan Haitian Biotechnology Co., Ltd. is a leading global supplier of Niclosamide CAS 50-65-7, a potent anthelmintic compound widely used in pharmaceuticals, agriculture, and research. Our product meets the highest international quality standards (ISO, GMP-certified) and is manufactured with precision to ensure purity (>99%), efficacy, and compliance with regulatory requirements.
Why Choose Our Niclosamide?
✅ High Purity & Quality Assurance: Rigorous testing ensures optimal performance for pharmaceutical and industrial applications.
✅ Competitive Pricing: Cost-effective solutions for bulk orders without compromising quality.
✅ Global Logistics: Fast, reliable shipping with secure documentation to your destination.
✅ Customized Solutions: Tailored packaging, formulations, and technical support to meet your needs.
Key Applications of Niclosamide CAS 50-65-7
Niclosamide is a versatile compound with proven efficacy in:
- Pharmaceuticals: Treatment of tapeworm infections (WHO-listed essential medicine).
- Agriculture: Eco-friendly pesticide for crop protection.
- Research: Studied for potential antiviral and anticancer properties.
- Water Treatment: Controls mollusk populations in aquaculture and water systems.
Technical Specifications
- CAS Number: 50-65-7
- Molecular Formula: C₁₃H₈Cl₂N₂O₄
- Purity: ≥99%
- Appearance: White to off-white crystalline powder
- Storage: Keep in a cool, dry place away from direct sunlight
Name Niclosamide
Synonyms Bayluscid; 2′,5-Dichloro-4′-nitrosalicylanilide; 2-Hydroxy-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide; 5-Chloro-2′-chloro-4′-nitrosalicylanilide; 5-Chloro-N-(2-chloro-4-nitrophenyl)salicylamide
Molecular Formula C13H8Cl2N2O4
Molecular Weight 327.12
CAS Registry Number 50-65-7
EINECS 200-056-8
Niclosamide is an antihelminthic used for the treatment of tapeworm infections. Helminths (worms) are multicellular organisms that infect very large numbers of humans and cause a broad range of diseases. Over 1 billion people are infected with intestinal nematodes, and many millions are infected with filarial nematodes, flukes, and tapeworms. They are an even greater problem in domestic animals.
Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.
Niclosamide is used for the treatment of most tapeworm infections. Helminths (worms) are multicellular organisms that infect very large numbers of humans and cause a broad range of diseases. Over 1 billion people are infected with intestinal nematodes, and many millions are infected with filarial nematodes, flukes, and tapeworms. They are an even greater problem in domestic animals.
Niclosamide is a member of benzamides.
Why Partner with Henan Haitian Biotechnology?
- Expertise: Over 15 years of experience in fine chemical manufacturing.
- Certifications: ISO 9001, GMP, and REACH compliance.
- Sustainability: Eco-conscious production processes.
- Customer Support: Dedicated team for technical guidance and after-sales service.
Frequently Asked Questions (FAQ)
Q: What is the lead time for Niclosamide orders?
A: Standard delivery is 7-14 days, with expedited options available.
Q: Do you offer sample requests?
A: Yes, we provide samples for quality verification.
Q: Is your Niclosamide suitable for GLP/GMP studies?
A: Absolutely—our product is ideal for research and commercial applications.
Order Niclosamide CAS 50-65-7 Today!
Henan Haitian Biotechnology Co., Ltd. is committed to delivering excellence. Contact us now for a quote, technical data sheets, or customized inquiries.
📞 Contact: +86-138-3717-8289 | ✉️ Email: haitianbiotech@gmail.com
