The Persistent Challenge of Schistosomiasis Schistosomiasis remains one of the most neglected tropical diseases worldwide, affecting hundreds of millions of people across Africa, Asia, and South America. Despite decades of control efforts, this parasitic infection continues to burden resource-limited communities where access to clean water and adequate sanitation remains scarce. For years, praziquantel has stood as the primary weapon against schistosomiasis. It works, it is relatively safe, and it does not break the bank. But the drug has its problems. Most notably, praziquantel shows reduced efficacy against juvenile worms, particularly those in the early stages of development. This creates a frustrating gap: infected individuals carry immature parasites that survive standard…