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Gut Bacteria Inactivate Flutamide: How Your Microbiome Could Sabotage Prostate Cancer Treatment
Prostate cancer is the second most common cancer in men worldwide. Androgen deprivation therapy has been the go-to treatment for decades. Flutamide, one of the earliest antiandrogen drugs, blocks the androgen receptor and starves tumors of the hormonal signals they need to grow. Here is the problem though: the drug does not work the same for everyone. Some patients respond well. Others barely at all. For a long time, nobody could explain why. The answer might have been living inside us the whole time. The gut microbiome: an overlooked metabolic organ There is growing evidence that the trillions of bacteria in the human gut do more than digest food. They…


